CYNAERA Institute
Predictive Research. Precision Frameworks. Systemic Repair.
The CYNAERA Institute is a systems intelligence research hub pioneering AI-powered models for infection-associated chronic conditions (IACCs), including, but not limited to ME/CFS, POTS, MCAS, and post-vaccine syndromes.
We build terrain-driven frameworks to map flare risk, stratify patients by remission potential, and power decentralized clinical trial design. This is research for those who’ve been ignored , and tools for the systems that failed them.
Our Research Pillars
Predictive Simulation- Synthetic cohorts modeled to test remission logic, gene edit impact, and flare forecasting.
Terrain Intelligence - Quantitative mapping of systemic burden using multi-biomarker and symptom cluster inputs.
Remission Science - Frameworks for identifying, accelerating, and validating pathways to recovery.
Stratified Trial Design - AI-informed subgroup targeting for precision enrollment in real-world conditions.
Featured Frameworks
CRISPR Remission™- AI-simulated gene editing models for multisystem remission targeting
Pathos™- Severity-based stratification system for IACCs across hormonal, age, and ancestry layers
VitalGuard™- Environmental risk forecaster for air-quality–sensitive populations
SymCas™- Symptom sequencing engine to detect pre-flare instability in remitting conditions
PULSE™- Narrative-anchored modeling for detecting underreported medical trends
CYNAERA Institute at a Glance
Remission, Simulated at Scale
Over 213 million synthetic patient journeys modeled using CYNAERA’s terrain-based intelligence. Each simulation charts flare progression, stabilization phases, and remission probabilities across multi-system conditions — from immune collapse to autonomic rebalancing.
Conditions Modeled and Mapped
79+ chronic illnesses, including:
Post-infectious conditions like Long COVID, ME/CFS, and Chronic Lyme
Neuroimmune and hormonal syndromes including POTS, MCAS, CRPS, Fibromyalgia
Autoimmune and environmentally triggered illnesses
Cancer-prone terrain profiles emerging from multisystem dysregulation
Current portfolio includes:
15 infection-associated conditions (IACCs)
10+ neuroinflammatory/hormonal diagnoses
3 pre-cancer terrain trajectories
Global Impact Potential
Between 325–375 million people worldwide could benefit from CYNAERA’s remission mapping, flare prediction, and trial stratification tools. That includes patients who remain misdiagnosed, undercounted, or excluded from traditional clinical models.
