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The Human Variable
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Composite Diagnostic Fingerprint for ME/CFS
The CDF-ME framework captures between 88–94% of patients who meet International Consensus Criteria (ICC), Canadian Consensus Criteria (CCC), or the National Academies of Sciences, Engineering, and Medicine (NASEM) diagnostic criteria, regardless of whether their illness was triggered by infection, vaccination, physical trauma, or environmental exposure. Validated through CYNAERA’s AI engine and over 200,000 patient simulations, CDF-ME integrates high-specificity markers .
May 14, 2025


A Nobel-Scale Advance: AI-Powered CRISPR Platform to End Infection-Associated Chronic Conditions - Lite
A Nobel-scale leap, built outside the system. This isn’t just another CRISPR project. CYNAERA’s AI-powered gene editing platform was designed by a patient, for patients—modeling remission across millions of synthetic profiles to restore immune stability in infection-associated chronic conditions like Long COVID, ME/CFS, and MCAS.
It cuts years off clinical trial timelines. It eliminates $5–10 million in early development costs. It’s scalable and ethical globally. AI meets bio
May 8, 2025


The Pathophysiology of Infection-Associated Chronic Conditions
Infection-associated chronic conditions (IACCs) such as Long COVID, ME/CFS, POTS, and MCAS are not disparate diagnoses — they are systemic sequelae following immune injury. For too long, medicine has treated these illnesses as anomalies or mysteries, when in fact, they follow a biologically predictable pattern of dysregulation.
Apr 29, 2025
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